Nuclear receptor ERR[alpha] and coactivator PGC-1[beta] are effectors of IFN- [gamma] induced host defence
Article Abstract:
The article describes that IFN [gamma] induces the expression of many nuclear genes encoding mitochondrial respiratory chain machinery through activation of the nuclear receptor ERR [alpha]. This shows that ERR[gamma] and PGC [beta] together act as a key effector of IFN- [gamma] induced mitochondrial ROS production and host defence.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function
Article Abstract:
The article discusses about mRNA surveillance stating that it helps to ensure the integrity of protein-coding gene expression along with the other types of quality control that occurs during the complex process of mRNA biogenesis.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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P21 transcription is regulated by differential localization of histone H2A.Z
Article Abstract:
The article describes that certain sequence-specific transcription factors regulates transcription, in part by preferentially positioning histone variant H2A.Z within chromatin.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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